Advocate™ Ultra Chew
Advocate Ultra Chew offers the broadest spectrum parasite protection*^ against ticks, fleas, demodex mites, heartworm disease and intestinal worms including tapeworms. Safe for puppies from 8 weeks of age and 2 kg, Advocate Ultra Chew is a convenient and tasty monthly solution for comprehensive parasite protection.
Why choose Advocate Ultra Chew for your dog?

Broadest spectrum of parasite protection*^
Convenience and peace of mind
The only all-in-one* that kills tapeworms
Protects dogs and families against dangerous zoonotic diseases

Fastest acting flea and tick protection*1-5
Quickest relief for dogs
Advocate Ultra Chew product details

Advocate Ultra Chew product details
Parasite protection: Fleas, ticks, demodex mites, roundworms, hookworms, tapeworms and heartworm disease
Pet type: Dogs and puppies
Application type: Chewable tablet
Flavour: Beef (vegetable-based formulation)
Dosage: Monthly
Sizes available: Advocate Ultra Chew comes in five different weight ranges to suit dogs from 2 kg and 8 weeks of age:
• XS 2 - 2.8 kg • L 11.1 - 22 kg
• S 2.9 - 5.5 kg • XL 22.1 - 45 kg
• M 5.6 - 11 kg
Dogs above 45 kg; use the appropriate combination of whole tablets
What does Advocate Ultra Chew protect against?

What does Advocate Ultra Chew protect against?
- Ticks: paralysis ticks, bush ticks, brown dog ticks
- Fleas: Eliminates existing fleas, kills reinfesting fleas and prevents flea tapeworm infestations
- Heartworm: Prevents heartworm disease
- Tapeworms: Treats and controls hydatid tapeworm, flea tapeworm and Taenia spp.
- Other Intestinal Worms: Treats and controls adult and juvenile roundworms and hookworms
- Mites: Treats and controls demodex mites
How does Advocate Ultra Chew work?

How does Advocate Ultra Chew work?
Active Ingredients: A combination of 4 well-established active ingredients – lotilaner, moxidectin, pyrantel and praziquantel.
Fastest-Acting Tick and Flea Protection: Advocate Ultra Chew provides the quickest relief for dogs, starting to kill fleas within 2 hours1 and ticks~ within 4 hours after dosing3.
One Month of Coverage: Advocate Ultra Chew keeps your dog protected for a full month. For the best protection, use Advocate Ultra Chew year-round.
Advocate Ultra Chew is trusted, tested and well tolerated

Advocate Ultra Chew is trusted, tested and well tolerated
- Safe for puppies from 8 weeks of age and >2kg
- Safe in avermectin-sensitive collies
- Safe in heartworm positive dogs
Adverse reactions to Advocate Ultra Chew are unlikely, however, if you have any concerns, please Contact Us here or speak to your veterinarian.
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*Of all canine all-in-one products that protect against fleas, ticks, heartworm and intestinal worms. ^Based on number of parasite species controlled. ~Ixodes ricinus
It’s recommended, in accordance with good veterinary practice, that all animals ≥ 6 months of age be tested for existing heartworm infections before beginning medication with Advocate Ultra Chew. As with all medications, it is recommended to check your pet for ticks daily.
References:
- Cavalleri, D. et al. (2017). Assessment of the onset of lotilaner (Credelio™) speed of kill of fleas on dogs. Parasit Vectors. 10(1):521
- Cavalleri, D. et al. (2017). Assessment of the speed of flea kill of lotilaner (Credelio™) throughout the month following oral administration to dogs. Parasit Vectors. 10(1):529
- Murphy, M. et al. (2017). Laboratory evaluation of the speed of kill of lotilaner (Credelio™) against Ixodes ricinus ticks on dogs. Parasit Vectors. 10(1):541
- Reif, K. et al. (2024). Comparative speed of kill provided by lotilaner (Credelio™), sarolaner (Simparica Trio™), and afoxolaner (NexGard™) to control Amblyomma americanum infestations on dogs. Parasit Vectors. 17(1):31
- Lyons R. et al. (2025, November 6–7), Speed-of-kill comparison of isoxazolines in the combination endectocide products Credelio™ PLUS (lotilaner), NexGard Spectra® (afoxolaner) and Simparica® Trio (sarolaner) against the Australian paralysis tick (Ixodes holocyclus) throughout one month. [Poster session] 1st Asia Pacific Veterinary Parasitology Congress (APAVP), Kuala Lumpur, Malaysia
Read the product leaflet for full instructions.
Download the product Safety Data Sheet.
For further information contact: 1800 995 709 from anywhere in Australia, Monday to Friday or email productsupportau@elancoah.com.
Advocate, Elanco and the diagonal bar or logo are trademarks of Elanco or its affiliates. ABN 64 076 745 198. Level 3, 7 Eden Park Drive, Macquarie Park NSW 2113.
