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This webpage is exclusively for pet owners with a prescription for Zenrelia™ from their veterinary professional. The content is appropriate for owners in both the UK and Ireland; this may vary for content outside this page. We are required by law to only provide information about Elanco products for which customers have a valid prescription. 

If you do not have a prescription, please visit the main My Pet & I site.

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Relieving your dog’s itch with Zenrelia™

Why has your vet prescribed Zenrelia for your dog?

Following your vet consultation, your vet has prescribed a new medicine called Zenrelia to help relieve your dog’s itchy skin. Your vet may have explained that there are four common forms of allergic itch in dogs:1,2

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    Canine Atopic Dermatitis (CAD), caused by allergies to environmental triggers such as pollen or house dust mites.
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    An allergy to parasites, such as fleas.
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    A food allergy, often to protein sources such as beef, dairy, chicken or pork in your dog’s food.
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    Contact allergies to substances your dog may come into contact with, including plants and cleaning products.
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What is Zenrelia?

Your vet has prescribed Zenrelia for your furry friend because it is an innovative treatment, providing relief from itch and treating the underlying inflammation in your dog’s skin. The small, unflavoured, once-daily tablet can be given with or without food.

Labrador scratching

Now that your vet has prescribed Zenrelia, here are three ways it helps your dog:3

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Reduces your dog's itch, fast.

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Improves their skin condition.

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Keeps them comfortable long-term.

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How to open a Zenrelia blister pack

Giving your dog Zenrelia

Complete Zenrelia tablet

The tablets are hypoallergenic and free of flavour additives that could trigger food allergies.4

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The tablets have a dividing line so can be split in half for doses involving half a tablet.

Zenrelia can be given with commonly used medications such as vaccines, antibiotics, parasite treatments and NSAIDs (non-steroidal anti-inflammatory drugs used to reduce pain and inflammation) but always follow the advice from your vet before doing so.4

If you have any questions about Zenrelia, please speak to your vet.

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What can you do at home to help manage your dog’s allergies?2,5

There are several ways you can help your dog’s skin health, comfort and quality of life. For this to work well, speak to your vet about a long-term management plan.

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    Give medications prescribed by your vet

    For many dogs, medications prescribed by your vet are key to managing their allergy. Make sure you follow your vet’s instructions.

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    Prevent parasites

    Fleas, ticks and mites are common causes of itching, so follow the advice from your vet on the most appropriate parasite protection plan for your dog.

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    Groom regularly

    This helps remove environmental allergens, such as pollen, from your dog’s skin after they’ve been outside. Speak to your vet about the most suitable grooming regime for your dog.

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    Provide a supportive diet

    Some foods and supplements, such as essential fatty acids, can improve your dog’s skin health. Ask your vet for recommendations.

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    Watch for signs

    Contact your vet early if you notice an itch flare-up (scratching, licking or rubbing), and/or areas of sore or red skin.

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Track your dog's itch relief

Your vet will have given you some information about Zenrelia, along with an itch tracker. Use this itch tracker to see how your dog’s itch level improves over time. It will also help your vet understand how well Zenrelia is working for your dog.


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Zenrelia™ Package Leaflet

Your dog has been prescribed Zenrelia tablets by the vet. View and download the Zenrelia package leaflet using the link below.

  1. Olivry T, et al. Vet Clin North Am Small Anim Pract. 1990;20(6):1443–56. 
  2. Miller J, et al. J Am Anim Hosp Assoc. 2023;59(6):255–284. 
  3. Forster S et al. Vet Dermatol 2025; Apr;36 (2):165-176.
  4. Zenrelia Summary of Product Characteristics. 
  5. University of Nottingham. The Itchy Dog Project – Identifying the appropriate treatment. Accessed February 2025. 

Brought to you by Elanco, makers of Zenrelia.

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PM-UK-25-0313

Date of review: August 2025

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